Redefining the Small Regulatory RNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39

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Identification and characterization of noncoding small RNAs in Streptococcus pneumoniae serotype 2 strain D39.

We report a search for small RNAs (sRNAs) in the low-GC, gram-positive human pathogen Streptococcus pneumoniae. Based on bioinformatic analyses by Livny et al. (J. Livny, A. Brencic, S. Lory, and M. K. Waldor, Nucleic Acids Res. 34:3484-3493, 2006), we tested 40 candidates by Northern blotting and confirmed the expression of nine new and one previously reported (CcnA) sRNAs in strain D39. CcnA ...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2019

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.00764-18